Because I have been taking supplements of many kinds for years, I was curious how much of a difference this would make. I have never been able to sit cross legged or with my legs "curled" up on a sofa because they'd "fall asleep" pretty quickly. But otherwise I have no circulation issues. Fast forward three weeks after I started taking this, I sat down with my laptop on the bed in my hotel room because the chair at the desk was uncomfortable. I thought I would just do some work quickly before my legs would start tingling. I did the quick task, then something else, then another thing. Before I knew it I had spent four and a half hours working and my legs still weren't tingling. I was shocked to say the least. For me to be able to sit like that in my mid-fifties for the first time in my life, that's quite remarkable. This really seems to have done the "trick."