Sulforaphane+
Rated 4.8 out of 5 stars
4.8 Stars (112 Reviews)
Supports Detoxification*
Promotes Antioxidant Activity*
Optimized with MyroActiv and Moringa
A phytochemical found in green vegetables responsible for many health benefits associated with eating broccoli, kale, and other cruciferous vegetables.*
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Sulforaphane+
suhl-fo-ruh-fayn
Sulforaphane is thought to be the main phytochemical behind the numerous health benefits associated with eating broccoli, kale, and other cruciferous vegetables.
the best benefits of broccoli, encapsulated*
Activates the NRF2 Pathway
The NRF2 Pathway is a master regulator of genes, activating genes to release powerful antioxidants that combat stress and inflammation in cells, helping to keep cells youthful and vibrant.*
Powerful Detoxification
Sulforaphane is a powerful activator of phase 2 enzymes in the liver. These enzymes transform toxins into less harmful substances that can easily be removed from the body through urine, poop, and sweat.*
Supports Youth and Vitality
Inflammation is the critical factor responsible for accelerated aging. Sulforaphane provides immense anti-inflammatory support, helping to elevate health, energy levels, and cognitive function.*
Sulforaphane+
suhl-fo-ruh-fayn
the best benefits of broccoli, encapsulated*
Sulforaphane is thought to be the main phytochemical behind the numerous health benefits associated with eating broccoli, kale, and other cruciferous vegetables.
Activates the NRF2 Pathway
The NRF2 Pathway is a master regulator of genes, activating genes to release powerful antioxidants that combat stress and inflammation in cells, helping to keep cells youthful and vibrant.*
Powerful Detoxification
Sulforaphane is a powerful activator of phase 2 enzymes in the liver. These enzymes transform toxins into less harmful substances that can easily be removed from the body through urine, poop, and sweat.* Supports Youth and Vitality
Inflammation is the critical factor responsible for accelerated aging. Sulforaphane provides immense anti-inflammatory support, helping to elevate health, energy levels, and cognitive function.* A New Standard in Supplements
Impeccable Manufacturing Standards
Every Humanx supplement is manufactured in a CGMP certified facility, this means every supplement:
- Meets FDA quality standards
- Contains premium quality ingredients
- Crafted with exceptional processing methods
Third Party Testing
Humanx undergoes rigorous third-party testing because we value complete transparency and you can feel confident you know exactly what you're getting
Evidence Based Ingredients
Our ingredients are extensively studied with the world's leading scientists publishing their peer reviewed findings in the National Center of Biotechnical Information
References
- Arai Y, Martin-Ruiz CM, Takayama M, et al. Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians. EBioMedicine. 2015.
- Houghton CA. Sulforaphane: Its "Coming of Age" as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease. Oxid Med Cell Longev. 2019.
- Yoshida K, Ushida Y, Ishijima T, et al. Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury. World J Gastroenterol. 2015.
- Fahey JW, Zhang Y, Talalay P. Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc Natl Acad Sci USA. 1997.
- Fahey JW, Talalay P. Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes. Food Chem Toxicol. 1999.
- Zhang Y, Talalay P. Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic Phase 2 enzymes. Cancer Res. 1998.
- Boddupalli S, Mein JR, Lakkanna S, James DR. Induction of phase 2 antioxidant enzymes by broccoli sulforaphane: perspectives in maintaining the antioxidant activity of vitamins a, C, and e. Front Genet. 2012.
- Dinkova-Kostova AT, Fahey JW, Kostov RV, Kensler TW. KEAP1 and Done? Targeting the NRF2 Pathway with Sulforaphane. Trends Food Sci Technol. 2017.
- Armah C.N., Derdemezis C., Traka M.H., Dainty J.R., Doleman J.F., Saha S. Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: Evidence from randomised controlled trials. Molecular Nutrition Food Research. 2015.
- Dinkova-Kostova A.T., Abramov A.Y. The emerging role of NRF2 in mitochondrial function. Free Radical Biology and Medicine. 2015.
- Fahey J.W., Wehage S.L., Holtzclaw W.D., Kensler T.W., Egner P.A., Shapiro T.A. Protection of humans by plant glucosinolates: Efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora. Cancer Prevention Research. 2012.
- Hayes J.D., Dinkova-Kostova A.T. The NRF2 regulatory network provides an interface between redox and intermediary metabolism. Trends in Biochemical Sciences. 2014.
- Kubo, E., Chhunchha, B., Singh, P. et al.Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress. Sci Rep. 2017.
- Bai Y, Wang X, Zhao S, Ma C, Cui J, Zheng Y. Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation. Oxid Med Cell Longev. 2015.
- Xianglan Zhang, Xiao-Ou Shu, Yong-Bing Xiang, Gong Yang, Honglan Li, Jing Gao, Hui Cai, Yu-Tang Gao, Wei Zheng, Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality, The American Journal of Clinical Nutrition. 2011.
- Evans PC. The influence of sulforaphane on vascular health and its relevance to nutritional approaches to prevent cardiovascular disease. EPMA J. 2011.
- Murashima M, Watanabe S, Zhuo XG, Uehara M, Kurashige A. Phase 1 study of multiple biomarkers for metabolism and oxidative stress after one-week intake of broccoli sprouts. Biofactors. 2004.
- Liu H, -J, Wang L, Kang L, Du J, Li S, Cui H, -X: Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells. Cell Physiol Biochem. 2018.
- Kim J, Lee S, Choi BR, Yang H, Hwang Y, Park JH, LaFerla FM, Han JS, Lee KW, Kim J. Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways. Mol Nutr Food Res. 2017.
- Zhang HQ, Chen SY, Wang AS, et al. Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization. Mol Nutr Food Res. 2016.
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